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For example, BTEX was reduced from 1200 to 380 mg|liter at a monitoring well 83 ft from the infiltration wells. , 487 STEC, 486 Infectious transfer see Horizontal gene transfer Inflammatory response: cutaneous, 5001 to lipopolysaccharide, 6556 Influenza: emerging, 10901 pandemic, 10901, 10956 antigenic drift, 1094 origins, 1096 Influenza vaccine, 10667 Influenza virus, reassortment in, 1080 Information, definition of, 251 Information Systems for Biotechnology, 529, 534 Inh protein, 1029 Inner mitochondrial membrane, 395 charge movement across, 397 Inoculation, definition of, 715 Myo-inositol, 758 Di-myo-inositol-1-1-phosphate (DIP), 759, 760 Inoviridae, 137, 138, 140, 145 Insect cell culture, definition of, 189 Insertion sequences see under Transposable elements Integrase, 38, 39 Integrase, definition of, 135 Integrating plasmid, definition of, 126 Integration host factor (IHF), 991 Integration host factor (IHF) bending protein, 266 Integrons, 389, 10345 diversity of, 40 Intelligence, definition of, 251 Interferons: adverse effects, 978 antisense RNA-induced, 756 chemistry|mechanism|activity, 97 clinical indications, 97 definition, 84 Internalin, 8 International Endotoxin Society, 645 International Food Biotechnology Council, 528 International Health Regulations, 387, 3923 Internet: genomic resources, 376 stock culture collections, 300 surveillance systems, 1099 see also Websites Interproximal, definition of, 739 Interspecies hydrogen transfer, definition of, 381, 659 Interspecific protoplase fusion, definition of, 960 Interstitial nephritis, definition of, 84 Intimin, 408 Invasin, 8, 412 Invasin, definition of, 1 Inverted repeats (IRs), 10256 definition, 1025 terminal sequences, 10256 Ion channels, 764 Ion gradients, 228 transporters coupled to, 2324 Ionizing radiation and DNA damage, 341, 342 Iron: in bioluminescence, 185 in nodule formation, 723 requirements|functions in microbes, 7312 Iron availability, 637 Iron metabolism, 63744 consensus sequences, 638 intracellular iron, free|stored, 6423 low affinity transport, 6412 pathogenicity, 6434 primary refueling reactions, 643 regulation, iron-dependent, 642 transport systems, 638 high affinity, 638 uptake, 63742 ferrous|ferric ions, 640 from heme, 641 siderophore-mediated systems, 63840 from transferrin|lactoferrin, 641 Iron-oxidizing bacteria, 643 Isoconazole, 55 Isoreceptors, definition of, 1 Isoschizomers, 368 Itraconazole, 578, 512 drug interactions, 57 side effects, 58 structure, 50 Japanese encephalitis vaccine, 1067 JarischHerxheimer reaction, 896 Kaposis sarcoma-associated virus, 10856 Karyogamy, 1111 KDEL retention signal sequence, 432 Kdo, definition of, 767 Kdo-Lipid A, 768, 772 Keratin, definition of, 499 Ketoconazole, 556 pharmacokinetics, 56 structure, 50 Khafrefungin, 66 Knockout mice, definition of, 829 Kochs postulates, 382 definition, 381 Korean hemorrhagic fever, 1089 KP-103, 61 Kpd proteins, 757 Kuru, 837, 839 L 743872 see Caspofungin LacI repressor protein, 988 -Lactam antibiotic resistance, 312 -Lactamase genes, 312 mutation, 31 -Lactamase inhibitors, 312 -Lactamases: Bacteroides fragilis, 559 origins, 41 Lactic acid bacteria: antibiotic resistance, 35 in esophagus|stomach, 517 Lactobacillus, oral, 744, 749 Lactoferrin (LF), definition of, 637 Lactose-proton transporter, 397 Lactose transport, 2334 lacZ gene: cloning of, 871 as probe, 872 Lamellar bilayer, 225 Lamivudine, 101 Land treatment, 202, 21011 definition, 196 LanderWaterman calculation, 374 plot, 375 Langerhans cells, 900 Lanoconazole, 55 las genes, 861 Laser scanning confocal microscope, definition of, 381 Lassa fever, 10878 Latent infections: fungal, 509 herpesvirus, 10801 1132 index Leader peptide, 11920 definition, 117 Leader peptide coding region, 119, 120 definition, 117 Learning, definition of, 251 Lectins: definition, 1 in nodule formation, 718 Leeches, 911 Legionella infection, 389 Legionella pneumophila virulence factors, 19, 20 Leguminosae phylogeny, 716 Lentiviruses, 1078 Leucine-responsive regulatory protein (Lrp), 468 Leukopenia, definition of, 84 Leviviridae, 137, 138, 140 LexA protein, 345 cleavage mechanism, 9301 as SOS regulator, 928 as SOS repressor, 92830 Liebigs principle, 726, 730 Life cycle, definition, 789 Ligation, 369 definition, 340, 870 Ligation|self-ligation, 872 Lincosamide resistance, 301 Linking clones, 540, 541 definition, 536 Lipid A: biosynthetic pathway, 772 definition, 645 microheterogeneity, 646 structure, 6458 synthesis, 648, 651 Lipid bilayer, definition of, 767 Lipids: of acidophiles, 441 of hyperthermophiles, 4389 Lipooligosaccharide (LOS), 569, 570, 571, 886 biosynthesis|assembly, 6512 definition, 645 molecular memory, 657 structure, 646, 647, 650 Lipopolysaccharide (LPS), 64558 barrier function, 771 biogenesis, 7723 topology, 773 biosynthesis|assembly, 6504 lipid A synthesis, 651 lipooligosaccharide, 6512 O polysaccarides, 6514 terminal reactions, 654 biotechnical applications, 657 definition, 645, 767 and enteric infections, 407, 524 functions|activities: in gram-negative sepsis, 6557 molecular memory, 657 in outer membrane stability, 654 as protective barrier, 6545 introduction, 645 neutralization, 657 pathogenic Neisseria, 56971 genetics of synthesis, 569 molecular mimicry, 570 structure, 64550, 7689 core oligosaccharides, 6489 lipid A, 6458 lipooligosaccharide, 650 O polysaccarides, 650 visualization in SDS-PAGE, 650 Lipoproteins: definition, 239 export, 849 in general secretion pathway, 843 Lipothrixviridae, 137, 138, 140 Listeria monocytogenes, 413 detection in food, 827 food-borne disease, 481, 48990 mortality rate, 490 Lithotrophs, 696, 726 definition, 690 Liver abscesses, 524 LN-2 adhesin binding, 7 Long terminal repeats see LTR Lopinavir|ritonavir, 106 Low transducing lysates, 1001 LTR (long terminal repeats): definition, 591 HIV, 593, 594 Luciferase: bacterial, 181, 182 structure, 183 definition, 180 dinoflagellate, 181, 186 genes, 180 Luciferin: definition, 180 dinoflagellate, 186 oxidation, 180 lux genes, 1834 in quorum sensing, 8601 Lux proteins, 866 Lux-type box, definition of, 859 LuxI-type proteins, 8623 LuxRLuxI proteins, 862, 863 LuxRLuxI-type proteins, 861 LuxR-type proteins, 864, 868 modular structure, 864 as repressors, 865 LuxR-type receptors, 861, 862, 863, 8656 LY 121019 see Cilofungin LY 303366 see Anidulafungin Lymphangitis, definition of, 899 Lymphocytes in viral infection, 1063 priming, 1064 Lymphogranuloma venerum, 888 Lyophilization, 618 definition, 294 Lysogenic bacteria: definition, 939 in space flight, 939 Lysogenic conversion, definition of, 415 Lysogeny, 1434, 337 definition, 1000 phage , 1039 Lysozyme, definition of, 239 Lytic phase, definition of, 927 Macrolide resistance, 301 genes from producers, 41 Macrophages, response to lipopolysaccharide, 656 Macrorestrictional mapping, definition of, 536 Magnesium, 731 Main terminal branch (MTB): exporters, 8512 shared homologies, 852 see also under Protein secretion|export Major 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